Pure Factors Premium Cellular ProFormance Complex 36 mg
What Do Growth Factors Do?
Insulin-like Growth Factors 1 and 2 (IGF-1 and IGF-2)
IGF-1 and IGF-2 increase lean body mass, reduce fat, build bone, muscle, and nerves while assisting in glucose metabolism. Research indicates that IGF-1 encourages the absorption of both chondroitin and glucosamine sulfate. Research also shows that a decline in IGF-1 levels is among the causes of bone disorder development. IGF-1 is considered by many scientists to be a marker in overall growth hormone status. IGF-1 looks and acts enough like insulin that your cell receptors may become suppressed, causing growth hormones to release stored fat. Through this mechanism, cells will use up fat rather than sugar or other carbohydrates. IGF-2 promotes tissue growth and is expressed primarily in embryonic and neonatal tissues.
Transforming Growth Factors A and B (TGF-A and TGF-B)
TGF-A promotes normal wound healing through a concerted effort with Epidermal Growth Factor and Platelet-Derived Growth Factor (PDGF). Without TGF-A, wound healing would be nearly impossible. TFG-B has an anti-inflammatory response to cytokine production and mesenchymal (MHC) expression. This promotes wound healing in a concerted effort with TGF-A, EGF and PDG while Inhibiting both macrophage and lymphocyte proliferation. Without TGF-B, wound healing would also be nearly impossible and an important “feedback loop” for cytokine anti-inflammatory production would not be in place. It is important to note that for normal tissue development to occur, whether it occurs through wound healing or regeneration, TGF A & B must be in a natural matrix of co-factors.
Growth factors (purple and yellow) bind to receptors (blue and green) that protrude from a cell’s surface. A cross-section view shows how the opposite end of each receptor reaches the inside of the cell (deep red area).
Vascular Endothelial Growth Factor (VEGF)
Promotes venous, venule, artery, arteriole and capillary health by providing the essential co-factors for repairing and restoring damaged vessels.
Works synergistically with nerve growth factor to promote neurite and nerve survival and development.
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